Article
The meiosis-specific zip4 protein regulates crossover distribution by promoting synaptonemal complex formation together with zip2.
Developmental cell - 1 Jun 2006
Tsubouchi Tomomi, Zhao Hongyu, Roeder G Shirleen
Abstract excerpt
We have characterized Zip4 (a.k.a. Spo22), a meiosis-specific protein essential for chromosome synapsis in budding yeast. In the absence of Zip4, the synaptonemal complex protein Zip1 fails to polymerize along chromosomes. Zip2 and Zip3 are previously characterized components of the synapsis initiation complex. Zip4 forms a functional unit with Zip2 that is distinct from Zip3. Zip2 and Zip4 are mutually dependent...
Topics
Join the communities discussing this publication.
