Article
A synaptonemal complex protein promotes homology-independent centromere coupling.
Science (New York, N.Y.) - 6 May 2005
Tsubouchi Tomomi, Roeder G Shirleen
Abstract excerpt
We describe a process in meiotic cells of budding yeast in which chromosomes become joined together in pairs at their centromeres independent of chromosomal homology. These centromeric interactions depend on the synaptonemal complex component Zip1. During meiosis in wild-type diploids, centromere couples are initially nonhomologous and then undergo switching until all couples involve homologs. This transition to...
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