Article
[Polymorphism of the microsatellites and tumor necrosis factor genes in chronic inflammatory bowel diseases].
Gastroenterologie clinique et biologique - 1 Jan 1997
Heresbach D, Ababou A, Bourienne A, Alizadeh M, Quelvennec E, Pagenault M, Dabadie A, Berre N H, Campion J P, Launois B, Gosselin M, Genetet B, Bretagne J F, Semana G
Abstract excerpt
OBJECTIVES: Multiplex family studies have excluded chromosome 6 as a candidate gene of susceptibility to inflammatory bowel disease. However, one recent study suggested that a gene involved in the pathogenesis of Crohn's disease is located on chromosome 6 confering to a microsatellite allelic combination (a2, b1, c2, d4, e1) a strong genetic risk factor in Crohn's disease. The aim of our study was to determine...
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