Article
Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6.
Gastroenterology - 1 Apr 1996
Plevy S E, Targan S R, Yang H, Fernandez D, Rotter J I, Toyoda H
Abstract excerpt
BACKGROUND & AIMS: HLA class II associations have been described in Crohn's disease (CD) and ulcerative colitis (UC) and may be markers for other closely linked genes that are involved in disease pathogenesis. The tumor necrosis factor (TNF) locus, which contains the genes for TNF-alpha and TNF-b...
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