The type of K-ras mutation determines prognosis in colorectal cancer.

doi:10.1016/s0002-9610(97)00283-3

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Article

The type of K-ras mutation determines prognosis in colorectal cancer.

American journal of surgery - 1 Mar 1998

Cerottini J P, Caplin S, Saraga E, Givel J C, Benhattar J

Abstract excerpt

BACKGROUND: Mutations involving the oncogene K-ras in colorectal cancer may be related to tumor aggressiveness. However, the value of K-ras gene determination as a prognostic marker has not been clearly established. PATIENTS AND METHODS: The results from 98 patients recruited in a prospective stu...

Topics

Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
Disease-Free Survival
Female
Genes, ras
Humans
Male
Middle Aged
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Prognosis
Prospective Studies
Survival Analysis

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