Article
A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Alcoholism, clinical and experimental research - 1 Apr 1998
Edenberg H J, Foroud T, Koller D L, Goate A, Rice J, Van Eerdewegh P, Reich T, Cloninger C R, Nurnberger J I, Kowalczuk M, Wu B, Li T K, Conneally P M, Tischfield J A, Wu W, Shears S, Crowe R, Hesselbrock V, Schuckit M, Porjesz B, Begleiter H
Abstract excerpt
The possible association of the DRD2 locus, and in particular the Taql-A1 allele, with alcoholism remains controversial, in part because of differences in allele frequencies among populations. To avoid problems associated with differences in allele frequencies in different populations, we tested...
Topics
- Alcoholism
- Alleles
- Chromosome Mapping
- Gene Frequency
- Humans
- Linkage Disequilibrium
- Models, Genetic
- Receptors, Dopamine D2
- Repetitive Sequences, Nucleic Acid
- Risk Factors