Article
A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Alcoholism, clinical and experimental research - 1 Apr 1998
Edenberg H J, Foroud T, Koller D L, Goate A, Rice J, Van Eerdewegh P, Reich T, Cloninger C R, Nurnberger J I, Kowalczuk M, Wu B, Li T K, Conneally P M, Tischfield J A, Wu W, Shears S, Crowe R, Hesselbrock V, Schuckit M, Porjesz B, Begleiter H
Abstract excerpt
The possible association of the DRD2 locus, and in particular the Taql-A1 allele, with alcoholism remains controversial, in part because of differences in allele frequencies among populations. To avoid problems associated with differences in allele frequencies in different populations, we tested whether the DRD2 locus is associated with alcohol dependence in a large family-based sample. Neither the...
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