Article
Linkage disequilibria at the D2 dopamine receptor locus (DRD2) in alcoholics and controls.
Genomics - 1 Jan 1994
Suarez B K, Parsian A, Hampe C L, Todd R D, Reich T, Cloninger C R
Abstract excerpt
Because of its central role in the neuromodulation of appetitive behaviors, the D2 dopamine receptor gene (DRD2) has received considerable scrutiny as a possible candidate that may affect susceptibility to additive behaviors--especially alcoholism. Association studies that compare the frequencies...
Topics
- Adult
- Alcoholism
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Gene Frequency
- Genes
- Genetic Predisposition to Disease
- Humans
- Linkage Disequilibrium
- Middle Aged
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine