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Article

Antibody-directed superantigen-mediated T-cell killing of myeloid leukaemic cell line cells.

European journal of haematology - 1 Apr 1998

Gidlöf C, Carlson B, Dohlsten M, Tötterman T H

Abstract excerpt

Bacterial superantigens (SAgs) bound to MHC class II molecules on target cells are efficient activators of cytotoxic T cells expressing certain T cell receptor (TCR) Vbeta regions We described earlier that the specificity of the SAg Staphylococcus enterotoxin A (SEA) can be changed by introducing a D227A point mutation in the major MHC class II binding site and by genetically fusing the SEA mutant (SEAm) to...

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Share to Antibodies, Monoclonal
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leukemia, Myeloid

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Share to T-Lymphocytes, Cytotoxic

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Source

Identifiers

PMID: 9579876
DOI: 10.1111/j.1600-0609.1998.tb01029.x

Genes

SEA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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