Article
A natural mutation of the amino acid residue at position 60 destroys staphylococcal enterotoxin A murine T-cell mitogenicity.
Infection and immunity - 1 Aug 1995
Mahana W, al-Daccak R, Lévéillé C, Valet J P, Hébert J, Ouellette M, Mourad W
Abstract excerpt
A variety of techniques have been used to identify the amino acid residues of bacterial superantigens involved in their interactions with major histocompatibility complex (MHC) class II and T-cell receptor (TCR). In this study, we isolated a naturally mutated staphylococcal enterotoxin A (SEA) from three different Staphylococcus aureus strains, in which the amino acid at position 60 has been changed from aspartic...
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