Article
A natural mutation of the amino acid residue at position 60 destroys staphylococcal enterotoxin A murine T-cell mitogenicity.
Infection and immunity - 1 Aug 1995
Mahana W, al-Daccak R, Lévéillé C, Valet J P, Hébert J, Ouellette M, Mourad W
Abstract excerpt
A variety of techniques have been used to identify the amino acid residues of bacterial superantigens involved in their interactions with major histocompatibility complex (MHC) class II and T-cell receptor (TCR). In this study, we isolated a naturally mutated staphylococcal enterotoxin A (SEA) fr...
Topics
- Animals
- Antibodies, Monoclonal
- Base Sequence
- DNA Primers
- Enterotoxins
- HLA-D Antigens
- Humans
- In Vitro Techniques
- Interleukin-2
- Lymphocyte Activation
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mitogens
- Molecular Sequence Data