Article
W64R mutation in beta-3-adrenergic receptor gene and weight in a large population sample.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Apr 1998
O'Dell S D, Bolla M K, Miller G J, Cooper J A, Humphries S E, Day I N
Abstract excerpt
We have investigated the W64R (Trp64Arg) mutation in the beta-3-adrenergic receptor in 2270 healthy British males aged 50-61 y. The frequency of the rare R allele was 0.07 (95% confidence interval (CI) 0.06-0.08). The men showed an absence of association between W64R genotype and weight or height...
Topics
- Alleles
- Body Mass Index
- Body Weight
- Confidence Intervals
- Gene Frequency
- Genotype
- Humans
- Male
- Mass Screening
- Middle Aged
- Obesity
- Point Mutation
- Polymerase Chain Reaction
- Receptors, Adrenergic, beta
- Receptors, Adrenergic, beta-3
- United Kingdom