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Article

Lack of association between the Trp64 Arg mutation in the beta 3-adrenergic receptor gene and obesity in Japanese men: a longitudinal analysis.

The Journal of clinical endocrinology and metabolism - 1 Apr 1997

Nagase T, Aoki A, Yamamoto M, Yasuda H, Kado S, Nishikawa M, Kugai N, Akatsu T, Nagata N

Abstract excerpt

The beta 3-adrenergic receptor (beta 3AR) is implicated in the regulation of thermogenesis and lipolysis, and it is suggested that the Trp64 Arg mutation in this receptor may contribute to the development of obesity. To examine whether the Trp64 Arg mutation had any effect on body weight during a...

Topics

Adult
Body Mass Index
Body Weight
Diabetes Mellitus, Type 2
Gene Frequency
Heterozygote
Homozygote
Humans
Japan
Longitudinal Studies
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Obesity

Receptors, Adrenergic, beta

Reference Values

Source

Identifiers

PMID: 9100608
DOI: 10.1210/jcem.82.4.3872

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9100608-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Lack of association between the Trp64 Arg mutation in the beta 3-adrenergic receptor gene and obesity in Japanese men: a longitudinal analysis.PMID 9100608Read ↗

Prevalence of the Trp64Arg missense mutation of the beta3-adrenergic receptor gene in Japanese subjects.Semantic proximity Read ↗

The Trp(64)Arg polymorphism of the beta(3)-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: a longitudinal analysis.Semantic proximity Read ↗

A mutation in the beta 3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects.Semantic proximity Read ↗

A Trp 64 Arg mutation in the beta3-adrenergic receptor gene is not associated with moderate overweight in Japanese workers.Semantic proximity Read ↗

The significance of the Trp 64 Arg mutation of the beta3-adrenergic receptor gene in impaired glucose tolerance, non-insulin-dependent diabetes mellitus, and insulin resistance in Japanese subjects.Semantic proximity Read ↗

Clinical features associated with the homozygous Trp64Arg mutation of the beta3-adrenergic receptor: no evidence for its association with obesity in Japanese.Semantic proximity Read ↗

Beta(3)-adrenergic receptor gene variant is associated with upper body obesity only in obese Japanese-American men but not in women.Semantic proximity Read ↗

W64R mutation in beta-3-adrenergic receptor gene and weight in a large population sample.Semantic proximity Read ↗

A mutation of the beta 3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride.Semantic proximity Read ↗

The Trp64Arg polymorphism of the beta3-adrenergic receptor gene is associated with weight changes in obese Japanese men: a 4-year follow-up study.Semantic proximity Read ↗

Gln27Glu variant of the beta2-adrenergic receptor gene is not associated with obesity and diabetes in Japanese-Americans.Semantic proximity Read ↗

Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with body mass index.Semantic proximity Read ↗

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