Article
beta(3) Adrenergic receptor polymorphism and obesity-related phenotypes in hypertensive patients.
Obesity research - 1 Jan 2004
Hao Ke, Peng Shaojie, Xing Houxun, Yu Yunxian, Huang Aiqun, Hong Xiumei, Wang Yuanping, Chen Changzhong, Wang Binyan, Zhang Xuejun, Liu Jing, Zhu Guoying, Huo Yong, Chen Dafang, Zhao Xiaotao, Ronnenberg Alayne, Wu Di, Niu Tianhua, Xu Xiping
Abstract excerpt
OBJECTIVES: Obesity is a complex trait that is affected by both environmental and genetic risk factors. The beta(3) adrenergic receptor (ADRB3) is expressed in adipose tissue and plays a role in energy metabolism. A missense mutation on codon 64 of this gene (W64R) is associated with receptor malfunction. Previous studies examining the relation between this polymorphism and obesity produced inconsistent findings....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.