Article
Tyrosine hydroxylase gene in linkage disequilibrium with mood disorders.
Molecular psychiatry - 1 Mar 1998
Serretti A, Macciardi F, Cusin C, Verga M, Pedrini S, Smeraldi E
Abstract excerpt
We studied tyrosine hydroxylase (TH) gene variants in mood disorders using linkage disequilibrium techniques. One hundred and forty-five inpatients affected by bipolar (n = 88) and unipolar (n = 57) disorders, and 84 healthy controls, were typed for TH variants using polymerase chain reaction (PC...
Topics
- Adult
- Age of Onset
- Aged
- Alleles
- Bipolar Disorder
- Chromosomes, Human, Pair 11
- DNA
- DNA Mutational Analysis
- Depressive Disorder
- Female
- Genotype
- Humans
- Italy
- Linkage Disequilibrium
- Male
- Middle Aged
- Mood Disorders
- Nerve Tissue Proteins