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Article

Tyrosine hydroxylase gene in linkage disequilibrium with mood disorders.

Molecular psychiatry - 1 Mar 1998

Serretti A, Macciardi F, Cusin C, Verga M, Pedrini S, Smeraldi E

Abstract excerpt

We studied tyrosine hydroxylase (TH) gene variants in mood disorders using linkage disequilibrium techniques. One hundred and forty-five inpatients affected by bipolar (n = 88) and unipolar (n = 57) disorders, and 84 healthy controls, were typed for TH variants using polymerase chain reaction (PCR) amplification. TH was associated with mood disorder, with all affected subjects presenting an excess of TH*2 allele...

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PMID: 9577842
DOI: 10.1038/sj.mp.4000373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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