Article
Tyrosine hydroxylase gene associated with depressive symptomatology in mood disorder.
American journal of medical genetics - 28 Mar 1998
Serretti A, Macciardi F, Verga M, Cusin C, Pedrini S, Smeraldi E
Abstract excerpt
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of dopamine and norepinephrine. It may be involved in the pathophysiology of psychiatric disorders and positive associations have been reported for TH gene markers in mood disorders. While most replications failed to confirm t...
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