Article
Association and haplotype analysis at the tyrosine hydroxylase locus in a combined German-British sample of manic depressive patients and controls.
Psychiatric genetics - 1 Jan 1994
Körner J, Rietschel M, Hunt N, Castle D, Gill M, Nöthen M M, Craddock N, Daniels J, Owen M, Fimmers R
Abstract excerpt
Tyrosine hydroxylase (TH) is the key enzyme in the synthesis of catecholamines and may therefore be of aetiological relevance in the development of psychiatric illness. Hipolar affective disorder association studies, with restriction fragment length polymorphisms located in flanking regions of th...
Topics
- Alleles
- Base Sequence
- Bipolar Disorder
- England
- Female
- Germany
- Haplotypes
- Humans
- Male
- Minisatellite Repeats
- Molecular Sequence Data
- Tyrosine 3-Monooxygenase
- Wales