No evidence of linkage or association between tyrosine hydroxylase gene and affective disorder.

Abstract excerpt

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of dopamine and norepinephrine, and therefore is of significant interest as a candidate gene in studies of affective disorders. We have carried out the linkage study between the susceptibility gene for affective disorder and tetranucleotide polymorphism of TH gene in five Japanese pedigrees. In addition to the linkage approach, we have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adolescent
• Share to Aged
• Share to Alleles