No evidence of linkage or association between tyrosine hydroxylase gene and affective disorder.

doi:10.1016/0165-0327(95)00004-7

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Article

No evidence of linkage or association between tyrosine hydroxylase gene and affective disorder.

Journal of affective disorders - 17 May 1995

Kawada Y, Hattori M, Fukuda R, Arai H, Inoue R, Nanko S

Abstract excerpt

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of dopamine and norepinephrine, and therefore is of significant interest as a candidate gene in studies of affective disorders. We have carried out the linkage study between the susceptibility gene for affective disorder and t...

Topics

Adolescent
Adult
Aged
Alleles
Base Sequence
Bipolar Disorder
Child
Child, Preschool
Depressive Disorder
Female
Gene Expression
Gene Frequency
Genetic Linkage
Humans
Infant
Japan
Male
Middle Aged

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