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Article

Plasmid maintenance of derivatives of oriP of Epstein-Barr virus

1 Feb 1995

Abstract excerpt

oriP is the origin of plasmid replication of Epstein-Barr virus. Replication from oriP requires both the cis-acting elements (the family of repeats and the dyad symmetry element) and the viral origin-binding protein, EBNA-1. The ability of plasmids containing oriP to be maintained stably in EBNA-1-positive cells reflects the efficiency both of their replication and of their segregation each cell cycle. The...

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Identifiers

PMID: 7815506
DOI: 10.1128/jvi.69.2.1280-1283.1995

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Plasmid maintenance of derivatives of oriP of Epstein-Barr virusPMID 7815506Read ↗

Rep*: a viral element that can partially replace the origin of plasmid DNA synthesis of Epstein-Barr virus.Semantic proximity Read ↗

Epstein-Barr virus-derived plasmids replicate only once per cell cycle and are not amplified after entry into cellsSemantic proximity Read ↗

Establishment of an <i>oriP</i> Replicon Is Dependent upon an Infrequent, Epigenetic EventSemantic proximity Read ↗

The minimal replicator of Epstein-Barr virus oriP.Semantic proximity Read ↗

Initiation of DNA replication within oriP is dispensable for stable replication of the latent Epstein-Barr virus chromosome after infection of established cell lines.Semantic proximity Read ↗

Telomere Repeat Binding Factors TRF1, TRF2, and hRAP1 Modulate Replication of Epstein-Barr Virus OriPSemantic proximity Read ↗

Sequence requirements of the Epstein-Barr virus latent origin of DNA replicationSemantic proximity Read ↗

The Linking Regions of EBNA1 Are Essential for Its Support of Replication and TranscriptionSemantic proximity Read ↗

Metaphase Chromosome Tethering Is Necessary for the DNA Synthesis and Maintenance of <i>oriP</i> Plasmids but Is Insufficient for Transcription Activation by Epstein-Barr Nuclear Antigen 1Semantic proximity Read ↗

Maintenance of Epstein–Barr virus (EBV) <i>oriP</i> -based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1Semantic proximity Read ↗

Replication from <i>oriP</i> of Epstein-Barr Virus Requires Exact Spacing of Two Bound Dimers of EBNA1 Which Bend DNASemantic proximity Read ↗

EBNA1 can link the enhancer element to the initiator element of the Epstein-Barr virus plasmid origin of DNA replicationSemantic proximity Read ↗

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