Article
The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors.
Genes & development - 1 May 1998
vom Baur E, Harbers M, Um S J, Benecke A, Chambon P, Losson R
Abstract excerpt
Nuclear receptors can function as ligand-inducible transregulators in both mammalian and yeast cells, indicating that important features of control of transcription have been conserved throughout evolution. Here, we report the isolation and characterization of a yeast protein that exhibits proper...
Topics
- Animals
- Binding Sites
- COS Cells
- Fungal Proteins
- Humans
- In Vitro Techniques
- Ligands
- Mice
- Mutation
- Nuclear Proteins
- Receptors, Estrogen
- Receptors, Retinoic Acid
- Recombinant Fusion Proteins
- Retinoid X Receptors
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Transcriptional Activation