Article
Overexpression of p53 predicts shorter survival in diffuse type gastric cancer.
The British journal of surgery - 1 Aug 1998
Lee W J, Shun C T, Hong R L, Wu M S, Chang K J, Chen K M
Abstract excerpt
BACKGROUND: It has been suggested that p53 plays an important part in gastric carcinogenesis but the data remain inconclusive. METHODS: Alteration of the tumour suppressor gene p53 was prospectively investigated by immunohistochemistry in 168 primary gastric cancers. RESULTS: Positive staining, i...
Topics
- Adenocarcinoma
- Adult
- Aged
- Female
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Multivariate Analysis
- Mutation
- Prognosis
- Prospective Studies
- Stomach Neoplasms
- Survival Analysis
- Tumor Suppressor Protein p53