Article
Evaluation of FHIT gene alterations in ovarian cancer.
British journal of cancer - 1 Apr 1998
Buttitta F, Marchetti A, Radi O, Bertacca G, Pellegrini S, Gadducci A, Genazzani A R, Bevilacqua G
Abstract excerpt
The FHIT gene, recently cloned and mapped on chromosome 3p14.2, has frequently been found to be abnormal in several established cancer cell lines and primary tumours. As alterations of chromosome 3p are common events in ovarian cancers with breakpoint sites at 3p14.2, we decided to investigate th...
Topics
- Acid Anhydride Hydrolases
- Adolescent
- Adult
- Child
- Child, Preschool
- Chromosomes, Human, Pair 3
- Exons
- Female
- Gene Deletion
- Genes, Tumor Suppressor
- Humans
- Middle Aged
- Mutation
- Neoplasm Proteins
- Neoplasm Staging
- Ovarian Neoplasms
- Proteins
- RNA, Messenger