Article
Low CD83, but normal MHC class II and costimulatory molecule expression, on spleen dendritic cells from HIV+ patients.
AIDS research and human retroviruses - 10 Apr 1998
McIlroy D, Autran B, Clauvel J P, Oksenhendler E, Debré P, Hosmalin A
Abstract excerpt
Dendritic cells (DCs), which are the most potent antigen-presenting cells for T lymphocytes, are targets for HIV in vitro and in vivo. Antigen presentation by DCs has been suggested to be impaired during HIV infection; however, the extent to which DCs from HIV+ individuals are altered, particularly in lymphoid organs where T cell stimulation takes place, is not clear. To address this question, the levels of...
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