Article
Mature dendritic cells infected with herpes simplex virus type 1 exhibit inhibited T-cell stimulatory capacity.
Journal of virology - 1 Aug 2000
Kruse M, Rosorius O, Krätzer F, Stelz G, Kuhnt C, Schuler G, Hauber J, Steinkasserer A
Abstract excerpt
Mature dendritic cells (DC) are the most potent antigen-presenting cells within the entire immune system. Interference with the function of these cells therefore constitutes a very powerful mechanism for viruses to escape immune responses. Several members of the Herpesviridae family have provided examples of such escape strategies, including interference with antigen presentation and production of homologous...
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