Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.

Journal of virology - 1 Jun 2004

Larsson Marie, Babcock Ethan, Grakoui Arash, Shoukry Naglaa, Lauer Georg, Rice Charles, Walker Christopher, Bhardwaj Nina

Abstract excerpt

Dendritic cells (DCs), which are potent antigen-presenting cells (APCs), are used as adjuvants for the treatment of cancer and infectious diseases in human and nonhuman primates, with documented clinical efficacy. The hepatitis C virus (HCV)-chimpanzee model is the best available model for testing the immunotherapeutic effects of DCs in the setting of a chronic infection, as chimpanzees develop a persistent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to CD83 Antigen

Share to Dendritic Cells

Share to Immunoglobulins

Share to Leukocytes, Mononuclear

Share to Pan troglodytes

Source

Open in PubMed Open full text

Identifiers

PMID: 15163708
DOI: 10.1128/JVI.78.12.6151-6161.2004
PMCID: PMC416524

Genes

APC
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.PMID 15163708Read ↗

Analysis of peripheral blood dendritic cells as a non-invasive tool in the follow-up of patients with chronic hepatitis C.Semantic proximity Read ↗

Infection and dysfunction of circulating blood dendritic cells and their subsets in chronic hepatitis C virus infection.Semantic proximity Read ↗

Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C.Semantic proximity Read ↗

Monocyte-derived dendritic cells from chronic HCV patients are not infected but show an immature phenotype and aberrant cytokine profile.Semantic proximity Read ↗

Functional impairment of dendritic cells in patients infected with hepatitis C virus genotype 1 who failed peginterferon plus ribavirin therapy.Semantic proximity Read ↗

Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes.Semantic proximity Read ↗

Circulating plasmacytoid dendritic cells in acutely infected patients with hepatitis C virus genotype 4 are normal in number and phenotype.Semantic proximity Read ↗

Hepatitis C virus structural proteins do not prevent human dendritic cell maturation.Semantic proximity Read ↗

Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection.Semantic proximity Read ↗

Hepatitis C virus core protein impairs in vitro priming of specific T cell responses by dendritic cells and hepatocytes.Semantic proximity Read ↗

Modulation of dendritic cell function by persistent virusesSemantic proximity Read ↗

Impaired functional capacities of liver dendritic cells from murine hepatitis B virus (HBV) carriers: relevance to low HBV-specific immune responses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.