Article
Transient and heritable mutators in adaptive evolution in the lab and in nature.
Genetics - 1 Apr 1998
Rosenberg S M, Thulin C, Harris R S
Abstract excerpt
Major advances in understanding the molecular mechanism of recombination-dependent stationary-phase mutation in Escherichia coli occurred this past year. These advances are reviewed here, and we also present new evidence that the mutagenic state responsible is transient. We find that most stationary-phase mutants do not possess a heritable stationary-phase mutator phenotype, although a small proportion of...
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