Article
Transient mutators: a semiquantitative analysis of the influence of translation and transcription errors on mutation rates.
Genetics - 1 Nov 1991
Ninio J
Abstract excerpt
A population of bacteria growing in a nonlimiting medium includes mutator bacteria and transient mutators defined as wild-type bacteria which, due to occasional transcription or translation errors, display a mutator phenotype. A semiquantitative theoretical analysis of the steady-state composition of an Escherichia coli population suggests that true strong genotypic mutators produce about 3 x 10(-3) of the single...
Topics
- Bacteria
- DNA Repair
- DNA Replication
- Genotype
- Mutagenesis
- Phenotype
- Protein Biosynthesis
- Transcription, Genetic
