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Article

Colorectal and extracolonic cancer variations in MLH1/MSH2 hereditary nonpolyposis colorectal cancer kindreds and the general population.

Diseases of the colon and rectum - 1 Apr 1998

Lin K M, Shashidharan M, Ternent C A, Thorson A G, Blatchford G J, Christensen M A, Lanspa S J, Lemon S J, Watson P, Lynch H T

Abstract excerpt

PURPOSE: This clinical case review aimed to identify phenotypic variations in colorectal and extracolonic cancer expression between hereditary nonpolyposis colorectal cancer (HNPCC) families with MLH1 and MSH2 germline mutations and the general population. METHODS: Colorectal cancer onset and site distribution were compared among 67 members of MLH1 kindreds, 45 members of MSH2 kindreds, and 1,189 patients from...

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Source

Identifiers

PMID: 9559626
DOI: 10.1007/BF02235755

Genes

MSH2
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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