Article
Uncoupling protein-1 mRNA expression in obese human subjects: the role of sequence variations at the uncoupling protein-1 gene locus.
Journal of lipid research - 1 Apr 1998
Esterbauer H, Oberkofler H, Liu Y M, Breban D, Hell E, Krempler F, Patsch W
Abstract excerpt
Uncoupling protein-1 (UCP-1) activity in brown adipose tissue increases thermogenesis, contributes to facultative energy expenditure in humans, and has been implicated in the pathogenesis of rodent obesity. To determine genetic factors controlling UCP-1 expression in humans, we measured intra- and extraperitoneal UCP-1 mRNA abundance levels by a competitive RT-PCR method and compared expression levels with common...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
