Article
Additive effect of A-->G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Dec 1996
Clément K, Ruiz J, Cassard-Doulcier A M, Bouillaud F, Ricquier D, Basdevant A, Guy-Grand B, Froguel P
Abstract excerpt
OBJECTIVE: Obesity results from an imbalance between caloric intake and energy expenditure, which is partly genetically determined. We have investigated, using a PCR-RFLP assay, the effects on weight gain of two genetic variants of the uncoupling proteins and the beta 3-adrenoceptor, two major ex...
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