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Article

Therapeutic repair of mutated nucleic acid sequences.

Nature biotechnology - 1 Apr 1998

Woolf T M

Abstract excerpt

The principle of therapeutic nucleic acid repair has been demonstrated in cell-free and cell culture experiments, in which compounds bind to and repair mutated sequences, thereby treating the primary defects of genetic disease. The mechanisms used to promote repair are diverse, encompassing techniques related to antisense, triple-strand, and ribozymes. Therapeutic nucleic acid repair has the potential to revert...

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PMID: 9555723
DOI: 10.1038/nbt0498-341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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