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Article

pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants.

Genes & development - 15 Apr 1998

Haviv I, Matza Y, Shaul Y

Abstract excerpt

Hepatitis B virus (HBV) infects humans and causes a wide range of clinical manifestations, from acute hepatitis to hepatocellular carcinoma (HCC). The HBV genome contains multiple promoters with gene expression regulated predominantly by the cellular transcription initiation machinery. Accordingly, the HBV-encoded pX, the only known viral regulator, is a potent transcription coactivator. We investigated the...

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Source

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Identifiers

PMID: 9553050
DOI: 10.1101/gad.12.8.1217
PMCID: PMC316710

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants.PMID 9553050Read ↗

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HBV X Protein Alters the DNA Binding Specificity of CREB and ATF-2 by Protein-Protein InteractionsSemantic proximity Read ↗

Different regions of hepatitis B virus X protein are required for enhancement of bZip-mediated transactivation versus transrepression.Semantic proximity Read ↗

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