Article
Mutual functional antagonism of the simian virus 40 T antigen and the hepatitis B virus trans activator.
Journal of virology - 1 May 1991
Seto E, Yen T S
Abstract excerpt
The hepatitis B virus X protein (pX) trans activates transcription of a wide variety of viral and cellular genes, apparently by interacting with multiple cellular transcription factors. It has been shown previously that the simian virus 40 early-region gene products (large-T and small-t antigens) prevent trans activation by pX. We show here that this phenomenon can be ascribed solely to the large-T antigen and...
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