Article
No association of apolipoprotein epsilon 4 allele with schizophrenia even in cognitively impaired patients.
Schizophrenia research - 10 Mar 1998
Thibaut F, Coron B, Hannequin D, Segard L, Martin C, Dollfus S, Campion D, Frebourg T, Petit M
Abstract excerpt
Given the strong association of the apolipoprotein E (apoE) allele epsilon 4 (epsilon 4) with Alzheimer's disease or cognitive decline in elderly, we tested whether cognitive performance in schizophrenic subjects is associated with an increase in the frequency of the ApoE epsilon 4 allele. Our data indicate that in our sample: (1) there is no association between schizophrenia and the ApoE epsilon 4 allele; and...
Topics
- Adult
- Alleles
- Apolipoproteins E
- Case-Control Studies
- Chi-Square Distribution
- Cognition Disorders
- Female
- Genetic Markers
- Humans
- Male
- Middle Aged
