Article
Schizophrenic women with the APOE epsilon 4 allele have a worse prognosis than those without it.
Molecular psychiatry - 1 May 2001
Martorell L, Virgos C, Valero J, Coll G, Figuera L, Joven J, Pocoví M, Labad A, Vilella E
Abstract excerpt
The epsilon 4 allele of APOE is generally accepted to be a risk factor in Alzheimer's disease and it has been related to other neuropsychiatric disorders, including schizophrenia. The results of several case-control studies have been inconclusive. To shed more light on this issue we carried out an association study that compared the APOE common variant in a group of 365 schizophrenia patients and 584 controls. We...
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