Article
Apolipoprotein E type epsilon 4 allele frequency is increased in patients with schizophrenia.
Neuroscience letters - 29 Dec 1995
Harrington C R, Roth M, Xuereb J H, McKenna P J, Wischik C M
Abstract excerpt
Apolipoprotein E type epsilon 4 alleles are increased in both Alzheimer's disease (AD) and cortical Lewy body dementia, while the epsilon 2 allele has been associated as a protective factor against the development of dementia in AD. We have determined APOE genotype in schizophrenic patients coming to autopsy (age range 19-95 years). The allele frequencies in this group were: epsilon 2, 6.0%; epsilon 3, 67.9%; and...
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