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Article

Degeneration of the cerebellar granule cell layer in transgenic mice expressing genes of human foamy virus.

Neuropathology and applied neurobiology - 1 Feb 1998

Lampe J, Marino S, Rethwilm A, Aguzzi A

Abstract excerpt

Transgenic mice expressing various combinations of structural and regulatory genes of human foamy virus (HFV) develop a neurodegenerative syndrome. delta gpe transgenic mice (which express the auxiliary bel-1 and bet genes along with truncated forms of gag, pol, and env) develop a severe neurological syndrome consisting mainly of spastic tetraparesis and blindness, and show neuronal loss in the hippocampus and...

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Identifiers

PMID: 9549727
DOI: 10.1046/j.1365-2990.1998.00086.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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