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Article

Cerebellar pathology in transgenic mice expressing the pseudorabies virus immediate-early protein IE180.

The European journal of neuroscience - 1 Apr 2008

Tomioka Yukiko, Miyazaki Taisuke, Taharaguchi Satoshi, Yoshino Saori, Morimatsu Masami, Uede Toshimitsu, Ono Etsuro, Watanabe Masahiko

Abstract excerpt

Pseudorabies virus is an alphaherpesvirus causing fatal neurological diseases in animals. Pseudorabies virus carries a gene encoding immediate-early (IE) protein IE180, which controls the transcription of other viral and host cell genes. Previously, we reported that transgenic expression of IE180 in mice causes severe ataxia and cerebellar deformity. Here we identified profound abnormalities in adult IE180...

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PMID: 18412631
DOI: 10.1111/j.1460-9568.2008.06174.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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