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Article

Defective kinesin heavy chain behavior in mouse kinesin light chain mutants.

The Journal of cell biology - 20 Sept 1999

Rahman A, Kamal A, Roberts E A, Goldstein L S

Abstract excerpt

Conventional kinesin, kinesin-I, is a heterotetramer of two kinesin heavy chain (KHC) subunits (KIF5A, KIF5B, or KIF5C) and two kinesin light chain (KLC) subunits. While KHC contains the motor activity, the role of KLC remains unknown. It has been suggested that KLC is involved in either modulation of KHC activity or in cargo binding. Previously, we characterized KLC genes in mouse (Rahman, A., D.S. Friedman, and...

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Source

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Identifiers

PMID: 10491391
DOI: 10.1083/jcb.146.6.1277
PMCID: PMC2156125

Genes

KLC1
COP1
KLC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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