Article
Transverse formamide gradients as a simple and easy way to optimise DNA single-strand conformation polymorphism analysis.
Nucleic acids research - 1 May 1998
Paccoud B, Bourguignon J, Diarra-Mehrpour M, Martin J P, Sesboüé R
Abstract excerpt
Although widely used, the detection of DNA mutations by the single-strand conformation polymorphism (SSCP) method is often hampered by the need to examine a large set of electrophoretic conditions in order to select the one suited to the DNA sequence under study. We show here that the use of tran...
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