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Article

Role of Lys215 located in the fifth transmembrane domain of the AT2 receptor in ligand-receptor interaction.

Regulatory peptides - 2 Jan 1998

Pulakat L, Tadessee A S, Dittus J J, Gavini N

Abstract excerpt

Studies on ligand-receptor interaction of Angiotensin II (Ang II) receptor type 1 have shown that for peptidic ligands to bind this receptor they must interact via their C-terminal carboxylate group to the positively charged side chain of the Lysine residue 199 located in the fifth transmembrane domain of this receptor. In the Ang II receptor type AT2, this Lysine residue is conserved at position 215 in the fifth...

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PMID: 9537673
DOI: 10.1016/s0167-0115(97)01059-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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