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Article

Dispensability of p53 degradation for tumorigenicity and decreased serum requirement of human papillomavirus type 16 E6.

Molecular carcinogenesis - 1 Mar 1998

Inoue T, Oka K, Yong-Il H, Vousden K H, Kyo S, Jing P, Hakura A, Yutsudo M

Abstract excerpt

Certain types of human papillomavirus (HPV), such as types 16 and 18, are etiological agents for carcinogenesis of the uterine cervix. These HPVs have two oncogenes, E6 and E7, that have transforming activities in established murine cells. Tumorigenicity and decreased serum requirement for cell growth are conferred by the E6 gene, whereas anchorage-independent growth is mainly governed by the E7 gene. To...

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PMID: 9537653

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Dispensability of p53 degradation for tumorigenicity and decreased serum requirement of human papillomavirus type 16 E6.PMID 9537653Read ↗

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