Article
Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes
1 Jul 1993
Abstract excerpt
Human papillomaviruses (HPVs) contribute to the development of almost all cervical cancers, a common and often fatal human disease. The mechanisms by which the HPVs function in malignant progression appear to be related to the activity of the two viral oncoproteins, E6 and E7, which form complexes with several cell proteins normally involved in controlling cell growth. Of particular interest has been the...
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