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Article

Probing the Yeast Phase-Specific Expression of the CBP1 Gene in Histoplasma capsulatum

1 Apr 1998

Abstract excerpt

Histoplasma capsulatum is a pathogenic fungus that exists in two distinct forms. The saprophytic mycelial phase inhabits moist soil environments; once inhaled, hyphae and conidia convert to a unicellular yeast phase that is capable of parasitizing macrophage phagolysosomes. Yeasts cultures, but not mycelial cultures, release large quantities of a calcium-binding protein (CBP) which may be important in calcium...

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PMID: 9537376
DOI: 10.1128/jb.180.7.1786-1792.1998

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