Molecular cell biology and molecular genetics of Histoplasma capsulatum.

Abstract excerpt

Histoplasma capsulatum is a dimorphic ascomycete which is capable of producing a broad spectrum of disease ranging from mild asymptomatic, pulmonary illness to severe, life-threatening systemic mycosis. Regulatory mechanisms that use temperature and other environmental cues are paramount to the successful adaptation of the organism as an effective intracellular pathogenic yeast. Although the biochemistry and...

Topics

• Gene Expression Regulation, Fungal
• Histoplasma
• Histoplasmosis
• Humans
• Mutation
• Phagosomes
• Phenotype
• Temperature
• Virulence