Article
Monitoring phase-specific gene expression in Histoplasma capsulatum with telomeric GFP fusion plasmids
1 Dec 2000
Abstract excerpt
Dimorphism is an essential feature of Histoplasma capsulatum pathogenesis, and much attention has been focused on characteristics that are unique to the saprophytic mycelial phase or the parasitic yeast phase. Recently, we identified a secreted calcium-binding protein, CBP, that is produced in large amounts by yeast cells but is undetectable in mycelial cultures. In this study, the green fluorescent protein (GFP)...
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