Article
Phenotypic variation and intracellular parasitism by histoplasma Capsulatum.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 2000
Kügler S, Schurtz Sebghati T, Groppe Eissenberg L, Goldman W E
Abstract excerpt
The success of Histoplasma capsulatum as an intracellular pathogen depends completely on successful conversion of the saprophytic mycelial (mold) form of this fungus to a parasitic yeast form. It is therefore not surprising that yeast phase-specific genes and gene products are proving to be important for survival and proliferation of H. capsulatum within macrophages. In this study, we have focused on the role and...
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