Article
Kidney-specific chromosome transfer in genetic hypertension: the Dahl hypothesis revisited.
Kidney international - 1 Aug 2001
Churchill P C, Churchill M C, Bidani A K, Kurtz T W
Abstract excerpt
BACKGROUND: A central dogma in the field of essential hypertension research is that the genetic transmission of increased blood pressure is determined solely by the genotype of the kidney. This concept is based in large part on studies in experimental rat models of spontaneous hypertension in which transplantation of a kidney from a hypertensive strain into a normotensive strain was reported to increase blood...
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