Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients.

British journal of cancer - 1 Mar 1998

Hubbard A L, Moyes C, Wyllie A H, Smith C A, Harrison D J

Abstract excerpt

Increased cancer risk has been associated with functional polymorphisms that occur within the genes coding for the N-acetyltransferase enzymes NAT1 and NAT2. We detected two NAT1 polymorphisms in colorectal cancer patients by heteroduplex analysis. DNA sequencing revealed the wild-type sequence (NAT1*4) and two single base substitutions at adjacent positions 999 bp (C to T, NAT1*14) and 1000 bp (G to A, NAT1*15)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Base Sequence
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Gene Frequency

Share to Genetic Variation

Share to Genotype

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 9528834
DOI: 10.1038/bjc.1998.151
PMCID: PMC2150084

Genes

NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients.PMID 9528834Read ↗

Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas.Semantic proximity Read ↗

N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.Semantic proximity Read ↗

The association of NAT1 polymorphisms and colorectal carcinoma risk: evidence from 20,000 subjects.Semantic proximity Read ↗

A restriction fragment length polymorphism assay that differentiates human N-acetyltransferase-1 (NAT1) alleles.Semantic proximity Read ↗

N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: a pooled analysis of variations from 59 studies.Semantic proximity Read ↗

Association of NAT1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with NAT1*10.Semantic proximity Read ↗

Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma.Semantic proximity Read ↗

Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1.Semantic proximity Read ↗

Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations.Semantic proximity Read ↗

N-acetyltransferase 1*10 genotype in bladder cancer patients.Semantic proximity Read ↗

Detection of mutations and polymorphism of N-acetyltransferase 1 gene in Indian, Malay and Chinese populations.Semantic proximity Read ↗

N-acetyltransferase 1 in colon and rectal cancer cases from an industrialized area.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.