Article
N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients.
British journal of cancer - 1 Mar 1998
Hubbard A L, Moyes C, Wyllie A H, Smith C A, Harrison D J
Abstract excerpt
Increased cancer risk has been associated with functional polymorphisms that occur within the genes coding for the N-acetyltransferase enzymes NAT1 and NAT2. We detected two NAT1 polymorphisms in colorectal cancer patients by heteroduplex analysis. DNA sequencing revealed the wild-type sequence (...
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