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Article

N-acetyltransferase 1 in colon and rectal cancer cases from an industrialized area.

Journal of toxicology and environmental health. Part A - 1 Jan 2008

Roemer Hermann C, Weistenhofer Wobbeke, Lohlein Dietrich, Geller Frank, Blomeke Brunhilde, Golka Klaus

Abstract excerpt

Colon and rectal cancers are both associated with genetic as well as nutritional, occupational, and environmental factors. Aromatic amines and heterocyclic amines are established colorectal carcinogens. The polymorphic enzyme N-acetyltransferase 1 (NAT1) contributes to heterocyclic amine metabolism in the human colon. Thereby, NAT1 may influence the risk for development of colorectal cancer. The distribution of...

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Identifiers

PMID: 18569593
DOI: 10.1080/15287390801988582

Genes

NAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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