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Article

Kinetic analysis of zinc ligand mutants of mammalian protein farnesyltransferase.

Biochemistry - 31 Mar 1998

Fu H W, Beese L S, Casey P J

Abstract excerpt

Protein farnesyltransferase (FTase) is a zinc metalloenzyme that catalyzes the prenylation of several proteins that are important in cellular regulatory events. A specific residue of FTase, Cys299 in the beta subunit previously identified as essential for zinc binding and catalysis, had been tent...

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PMID: 9521766
DOI: 10.1021/bi972511c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-9521766-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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