Article
Role of the Zn(2+) motif of E1 in SUMO adenylation.
The Journal of biological chemistry - 30 Jul 2010
Wang Jianghai, Chen Yuan
Abstract excerpt
Post-translational modifications by ubiquitin-like proteins are among the most important mechanisms for regulating a wide variety of cellular functions. In these modifications an E1 enzyme activates each ubiquitin-like protein (Ubl) by adenylation of the Ubl C-terminal COOH group and then forms a...
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